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Physiologically relevant factors influence tau phosphorylation by Leucine-rich repeat kinase 2
Hyper-phosphorylation and aggregation of tau are observed in multiple neurodegenerative diseases, termed tauopathies. Tau has also been implicated in the pathogenesis of Parkinson’s disease (PD) and parkinsonisms. Interestingly, a subset of PD patients with mutations in the Leucine-rich repeat kinas...
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| Publicado no: | J Neurosci Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869353/ https://ncbi.nlm.nih.gov/pubmed/26123245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23614 |
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