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The Growth Suppressor PML Represses Transcription by Functionally and Physically Interacting with Histone Deacetylases

The growth suppressor promyelocytic leukemia protein (PML) is disrupted by the chromosomal translocation t(15;17) in acute promyelocytic leukemia (APL). PML plays a key role in multiple pathways of apoptosis and regulates cell cycle progression. The present study demonstrates that PML represses tran...

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Udgivet i:Mol Cell Biol
Principais autores: Wu, Wen-Shu, Vallian, Sadeq, Seto, Edward, Yang, Wen-Ming, Edmondson, Diane, Roth, Sharon, Chang, Kun-Sang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.7.2259-2268.2001
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