The Growth Suppressor PML Represses Transcription by Functionally and Physically Interacting with Histone Deacetylases

The growth suppressor promyelocytic leukemia protein (PML) is disrupted by the chromosomal translocation t(15;17) in acute promyelocytic leukemia (APL). PML plays a key role in multiple pathways of apoptosis and regulates cell cycle progression. The present study demonstrates that PML represses tran...

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Autores principales: Wu, Wen-Shu, Vallian, Sadeq, Seto, Edward, Yang, Wen-Ming, Edmondson, Diane, Roth, Sharon, Chang, Kun-Sang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC86860/
https://ncbi.nlm.nih.gov/pubmed/11259576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.7.2259-2268.2001
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