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Checkpoint Adaptation Precedes Spontaneous and Damage-Induced Genomic Instability in Yeast

Despite the fact that eukaryotic cells enlist checkpoints to block cell cycle progression when their DNA is damaged, cells still undergo frequent genetic rearrangements, both spontaneously and in response to genotoxic agents. We and others have previously characterized a phenomenon (adaptation) in w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Galgoczy, David J., Toczyski, David P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86717/
https://ncbi.nlm.nih.gov/pubmed/11238908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1710-1718.2001
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