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Checkpoint Adaptation Precedes Spontaneous and Damage-Induced Genomic Instability in Yeast

Despite the fact that eukaryotic cells enlist checkpoints to block cell cycle progression when their DNA is damaged, cells still undergo frequent genetic rearrangements, both spontaneously and in response to genotoxic agents. We and others have previously characterized a phenomenon (adaptation) in w...

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Detalhes bibliográficos
Main Authors: Galgoczy, David J., Toczyski, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86717/
https://ncbi.nlm.nih.gov/pubmed/11238908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1710-1718.2001
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