VAMP3 Null Mice Display Normal Constitutive, Insulin- and Exercise-Regulated Vesicle Trafficking

To investigate the physiological function of the VAMP3 vesicle SNARE (v-SNARE) isoform in the regulation of GLUT4 vesicle trafficking, we generated homozygotic VAMP3 null mice by targeted gene disruption. The VAMP3 null mice had typical growth rate and weight gain, with normal maintenance of fasting...

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Bibliografiske detaljer
Main Authors: Yang, Chunmei, Mora, Silvia, Ryder, Jeffrey W., Coker, Kenneth J., Hansen, Polly, Allen, Lee-Ann, Pessin, Jeffrey E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86703/
https://ncbi.nlm.nih.gov/pubmed/11238894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1573-1580.2001
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