VAMP3 Null Mice Display Normal Constitutive, Insulin- and Exercise-Regulated Vesicle Trafficking

To investigate the physiological function of the VAMP3 vesicle SNARE (v-SNARE) isoform in the regulation of GLUT4 vesicle trafficking, we generated homozygotic VAMP3 null mice by targeted gene disruption. The VAMP3 null mice had typical growth rate and weight gain, with normal maintenance of fasting...

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Main Authors: Yang, Chunmei, Mora, Silvia, Ryder, Jeffrey W., Coker, Kenneth J., Hansen, Polly, Allen, Lee-Ann, Pessin, Jeffrey E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC86703/
https://ncbi.nlm.nih.gov/pubmed/11238894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1573-1580.2001
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