Grb2 and Shc Adapter Proteins Play Distinct Roles in Neu (ErbB-2)-Induced Mammary Tumorigenesis: Implications for Human Breast Cancer

Amplification of the Neu (ErbB-2 or HER-2) receptor tyrosine kinase occurs in 20 to 30% of human mammary carcinomas, correlating with a poor clinical prognosis. We have previously demonstrated that four (Y1144 Y1201, Y1227 and Y1253) of the five known Neu autophosphorylation sites can independently...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Dankort, David, Maslikowski, Bart, Warner, Neil, Kanno, Nubufumi, Kim, Harold, Wang, Zhixiang, Moran, Michael F., Oshima, Robert G., Cardiff, Robert D., Muller, William J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86700/
https://ncbi.nlm.nih.gov/pubmed/11238891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1540-1551.2001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker