Mutational and Structural Analyses of the Ribonucleotide Reductase Inhibitor Sml1 Define Its Rnr1 Interaction Domain Whose Inactivation Allows Suppression of mec1 and rad53 Lethality

In budding yeast, MEC1 and RAD53 are essential for cell growth. Previously we reported that mec1 or rad53 lethality is suppressed by removal of Sml1, a protein that binds to the large subunit of ribonucleotide reductase (Rnr1) and inhibits RNR activity. To understand further the relationship between...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Zhao, Xiaolan, Georgieva, Bilyana, Chabes, Andrei, Domkin, Vladimir, Ippel, Johannes H., Schleucher, Jürgen, Wijmenga, Sybren, Thelander, Lars, Rothstein, Rodney
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2000
Aiheet:	Cell Growth and Development
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11074005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.9076-9083.2000
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