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Mouse ribonucleotide reductase R2 protein: A new target for anaphase-promoting complex-Cdh1-mediated proteolysis

Ribonucleotide reductase consists of two nonidentical proteins, R1 and R2, and catalyzes the rate-limiting step in DNA precursor synthesis: the reduction of ribonucleotides to deoxyribonucleotides. A strictly balanced supply of deoxyribonucleotides is essential for both accurate DNA replication and...

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Detalles Bibliográficos
Autores principales: Chabes, Anna Lena, Pfleger, Cathie M., Kirschner, Marc W., Thelander, Lars
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC153024/
https://ncbi.nlm.nih.gov/pubmed/12655059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0330774100
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