Mouse ribonucleotide reductase R2 protein: A new target for anaphase-promoting complex-Cdh1-mediated proteolysis

Ribonucleotide reductase consists of two nonidentical proteins, R1 and R2, and catalyzes the rate-limiting step in DNA precursor synthesis: the reduction of ribonucleotides to deoxyribonucleotides. A strictly balanced supply of deoxyribonucleotides is essential for both accurate DNA replication and...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Chabes, Anna Lena, Pfleger, Cathie M., Kirschner, Marc W., Thelander, Lars
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12655059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0330774100
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