Coupled Homologous and Nonhomologous Repair of a Double-Strand Break Preserves Genomic Integrity in Mammalian Cells

DNA double-strand breaks (DSBs) may be caused by normal metabolic processes or exogenous DNA damaging agents and can promote chromosomal rearrangements, including translocations, deletions, or chromosome loss. In mammalian cells, both homologous recombination and nonhomologous end joining (NHEJ) are...

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Argitaratua izan da:	Mol Cell Biol
Egile Nagusiak:	Richardson, Christine, Jasin, Maria
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis 2000
Gaiak:	DNA Dynamics and Chromosome Structure
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86559/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11074004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.9068-9075.2000
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