Coupled Homologous and Nonhomologous Repair of a Double-Strand Break Preserves Genomic Integrity in Mammalian Cells

DNA double-strand breaks (DSBs) may be caused by normal metabolic processes or exogenous DNA damaging agents and can promote chromosomal rearrangements, including translocations, deletions, or chromosome loss. In mammalian cells, both homologous recombination and nonhomologous end joining (NHEJ) are...

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Richardson, Christine, Jasin, Maria
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 2000
Onderwerpen:	DNA Dynamics and Chromosome Structure
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86559/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11074004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.9068-9075.2000
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!