Mice with an Increased Glucocorticoid Receptor Gene Dosage Show Enhanced Resistance to Stress and Endotoxic Shock

Targeted mutagenesis of the glucocorticoid receptor has revealed an essential function for survival and the regulation of multiple physiological processes. To investigate the effects of an increased gene dosage of the receptor, we have generated transgenic mice carrying two additional copies of the...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Reichardt, Holger M., Umland, Thorsten, Bauer, Anton, Kretz, Oliver, Schütz, Günther
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.9009-9017.2000
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!