Mice with an Increased Glucocorticoid Receptor Gene Dosage Show Enhanced Resistance to Stress and Endotoxic Shock

Targeted mutagenesis of the glucocorticoid receptor has revealed an essential function for survival and the regulation of multiple physiological processes. To investigate the effects of an increased gene dosage of the receptor, we have generated transgenic mice carrying two additional copies of the...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Reichardt, Holger M., Umland, Thorsten, Bauer, Anton, Kretz, Oliver, Schütz, Günther
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2000
Fag:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.9009-9017.2000
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