Proteasome-Mediated Degradation of the Coactivator p300 Impairs Cardiac Transcription

The transcription of tissue-specific genes is controlled by regulatory factors and cofactors and is suppressed in cardiac cells by the antineoplastic agent doxorubicin. Here we show that exposure of cultured cardiomyocytes to doxorubicin resulted in the rapid depletion of transcripts for MEF2C, dHAN...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Poizat, Coralie, Sartorelli, Vittorio, Chung, Gene, Kloner, Robert A., Kedes, Larry
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2000
Aiheet:	Transcriptional Regulation
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8643-8654.2000
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!