Proteasome-Mediated Degradation of the Coactivator p300 Impairs Cardiac Transcription

The transcription of tissue-specific genes is controlled by regulatory factors and cofactors and is suppressed in cardiac cells by the antineoplastic agent doxorubicin. Here we show that exposure of cultured cardiomyocytes to doxorubicin resulted in the rapid depletion of transcripts for MEF2C, dHAN...

Descrición completa

Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Poizat, Coralie, Sartorelli, Vittorio, Chung, Gene, Kloner, Robert A., Kedes, Larry
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2000
Assuntos:	Transcriptional Regulation
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8643-8654.2000
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!