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The Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire

In all of the transposition reactions that have been characterized thus far, synapsis of two transposon ends is required before any catalytic steps (strand nicking or strand transfer) occur. In V(D)J recombination, there have been inconclusive data concerning the role of synapsis in nicking. Synapsi...

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Autors principals: Yu, Kefei, Lieber, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86402/
https://ncbi.nlm.nih.gov/pubmed/11027262
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