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The Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire

In all of the transposition reactions that have been characterized thus far, synapsis of two transposon ends is required before any catalytic steps (strand nicking or strand transfer) occur. In V(D)J recombination, there have been inconclusive data concerning the role of synapsis in nicking. Synapsi...

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Detalhes bibliográficos
Main Authors: Yu, Kefei, Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86402/
https://ncbi.nlm.nih.gov/pubmed/11027262
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