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G Protein-Coupled Receptor-Mediated Mitogen-Activated Protein Kinase Activation through Cooperation of Gα(q) and Gα(i) Signals

G protein-coupled receptors (GPCRs) have been shown to stimulate extracellular regulated kinases (ERKs) through a number of linear pathways that are initiated by G(q/11) or G(i) proteins. We studied signaling to the ERK cascade by receptors that simultaneously activate both G protein subfamilies. In...

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Autores principales: Blaukat, Andree, Barac, Ana, Cross, Michael J., Offermanns, Stefan, Dikic, Ivan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC86218/
https://ncbi.nlm.nih.gov/pubmed/10958680
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