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Endogenous Gαq-coupled Neuromodulator Receptors Activate Protein Kinase A

Protein kinase A (PKA) integrates inputs from G protein-coupled neuromodulator receptors to modulate synaptic and cellular function. Gαs signaling stimulates PKA activity, whereas Gαi inhibits PKA activity. Gαq, on the other hand, signals through phospholipase C, and it remains unclear if Gαq-couple...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Chen, Yao, Granger, Adam J., Tran, Trinh, Saulnier, Jessica L., Kirkwood, Alfredo, Sabatini, Bernardo L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726796/
https://ncbi.nlm.nih.gov/pubmed/29154125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.10.023
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