Role of the LXCXE Binding Site in Rb Function
Oncoproteins from DNA tumor viruses such as adenovirus E1a, simian virus 40 T antigen, and human papillomavirus E7 contain an LXCXE sequence, which they use to bind the retinoblastoma protein (Rb) and inhibit its function. Cellular proteins such as histone deacetylases 1 and 2 (HDAC1 and -2) also co...
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| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.18.6799-6805.2000 |
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