Role of the LXCXE Binding Site in Rb Function

Oncoproteins from DNA tumor viruses such as adenovirus E1a, simian virus 40 T antigen, and human papillomavirus E7 contain an LXCXE sequence, which they use to bind the retinoblastoma protein (Rb) and inhibit its function. Cellular proteins such as histone deacetylases 1 and 2 (HDAC1 and -2) also co...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dahiya, Anjali, Gavin, Mark R., Luo, Robin X., Dean, Douglas C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2000
विषय:
Cell Growth and Development
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC86207/
https://ncbi.nlm.nih.gov/pubmed/10958676
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