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Role of the LXCXE Binding Site in Rb Function

Oncoproteins from DNA tumor viruses such as adenovirus E1a, simian virus 40 T antigen, and human papillomavirus E7 contain an LXCXE sequence, which they use to bind the retinoblastoma protein (Rb) and inhibit its function. Cellular proteins such as histone deacetylases 1 and 2 (HDAC1 and -2) also co...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Dahiya, Anjali, Gavin, Mark R., Luo, Robin X., Dean, Douglas C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86207/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958676/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.18.6799-6805.2000
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