The RNA-Binding Protein TIA-1 Is a Novel Mammalian Splicing Regulator Acting through Intron Sequences Adjacent to a 5′ Splice Site

Splicing of the K-SAM alternative exon of the fibroblast growth factor receptor 2 gene is heavily dependent on the U-rich sequence IAS1 lying immediately downstream from its 5′ splice site. We show that IAS1 can activate the use of several heterologous 5′ splice sites in vitro. Addition of the RNA-b...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Del Gatto-Konczak, Fabienne, Bourgeois, Cyril F., Le Guiner, Caroline, Kister, Liliane, Gesnel, Marie-Claude, Stévenin, James, Breathnach, Richard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Gene Expression
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86103/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938105/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6287-6299.2000
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