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SR proteins and hnRNP H regulate the splicing of the HIV-1 tev-specific exon 6D
A naturally arising point mutation in the env gene of HIV-1 activates the aberrant inclusion of the cryptic exon 6D into most viral messages, leading to inefficient viral replication. We set out to understand how a single nucleotide substitution could cause such a dramatic change in splicing. We hav...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125874/ https://ncbi.nlm.nih.gov/pubmed/11847131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.845 |
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