SR proteins and hnRNP H regulate the splicing of the HIV-1 tev-specific exon 6D
A naturally arising point mutation in the env gene of HIV-1 activates the aberrant inclusion of the cryptic exon 6D into most viral messages, leading to inefficient viral replication. We set out to understand how a single nucleotide substitution could cause such a dramatic change in splicing. We hav...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11847131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.4.845 |
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