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SR proteins and hnRNP H regulate the splicing of the HIV-1 tev-specific exon 6D

A naturally arising point mutation in the env gene of HIV-1 activates the aberrant inclusion of the cryptic exon 6D into most viral messages, leading to inefficient viral replication. We set out to understand how a single nucleotide substitution could cause such a dramatic change in splicing. We hav...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Caputi, Massimo, Zahler, Alan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC125874/
https://ncbi.nlm.nih.gov/pubmed/11847131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.845
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