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TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of stromelysin-1

TEL is a member of the ETS family of transcription factors that interacts with the mSin3 and SMRT corepressors to regulate transcription. TEL is biallelically disrupted in acute leukemia, and loss of heterozygosity at the TEL locus has been observed in various cancers. Here we show that expression o...

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Autori principali: Fenrick, Randy, Wang, Lilin, Nip, John, Amann, Joseph M., Rooney, Robert J., Walker-Daniels, Jennifer, Crawford, Howard C., Hulboy, Diana L., Kinch, Michael S., Matrisian, Lynn M., Hiebert, Scott W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86060/
https://ncbi.nlm.nih.gov/pubmed/10913166
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