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Rho-stimulated Contractility Contributes to the Fibroblastic Phenotype of Ras-transformed Epithelial Cells

Oncogenic transformation of cells alters their morphology, cytoskeletal organization, and adhesive interactions. When the mammary epithelial cell line MCF10A is transformed by activated H-Ras, the cells display a mesenchymal/fibroblastic morphology with decreased cell–cell junctions but increased fo...

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Autors principals: Zhong, Cuiling, Kinch, Michael S., Burridge, Keith
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC25711/
https://ncbi.nlm.nih.gov/pubmed/9362072
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