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Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily.

Although Ras residue phenylalanine-156 (F156) is strictly conserved in all members of the Ras superfamily of proteins, it is located outside of the consensus GDP/GTP-binding pocket. Its location within the hydrophobic core of Ras suggests that its strict conservation reflects a crucial role in struc...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Quilliam, L A, Zhong, S, Rabun, K M, Carpenter, J W, South, T L, Der, C J, Campbell-Burk, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7877967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1272
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