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Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily.

Although Ras residue phenylalanine-156 (F156) is strictly conserved in all members of the Ras superfamily of proteins, it is located outside of the consensus GDP/GTP-binding pocket. Its location within the hydrophobic core of Ras suggests that its strict conservation reflects a crucial role in struc...

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Autors principals: Quilliam, L A, Zhong, S, Rabun, K M, Carpenter, J W, South, T L, Der, C J, Campbell-Burk, S
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC42501/
https://ncbi.nlm.nih.gov/pubmed/7877967
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