Evidence for an Interaction between Ubiquitin-Conjugating Enzymes and the 26S Proteasome
The targeting of proteolytic substrates is accomplished by a family of ubiquitin-conjugating (E2) enzymes and a diverse set of substrate recognition (E3) factors. The ligation of a multiubiquitin chain to a substrate can promote its degradation by the proteasome. However, the mechanism that facilita...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4691-4698.2000 |
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