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Evidence for an Interaction between Ubiquitin-Conjugating Enzymes and the 26S Proteasome

The targeting of proteolytic substrates is accomplished by a family of ubiquitin-conjugating (E2) enzymes and a diverse set of substrate recognition (E3) factors. The ligation of a multiubiquitin chain to a substrate can promote its degradation by the proteasome. However, the mechanism that facilita...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Tongaonkar, Prasad, Chen, Li, Lambertson, David, Ko, Bom, Madura, Kiran
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85887/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4691-4698.2000
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