RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit
The RPN4 (SON1, UFD5) protein of the yeast Saccharomyces cerevisiae is required for normal levels of intracellular proteolysis. RPN4 is a transcriptional activator of genes encoding proteasomal subunits. Here we show that RPN4 is required for normal levels of these subunits. Further, we demonstrate...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2001
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248031/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071022298 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|