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RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit
The RPN4 (SON1, UFD5) protein of the yeast Saccharomyces cerevisiae is required for normal levels of intracellular proteolysis. RPN4 is a transcriptional activator of genes encoding proteasomal subunits. Here we show that RPN4 is required for normal levels of these subunits. Further, we demonstrate...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30606/ https://ncbi.nlm.nih.gov/pubmed/11248031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071022298 |
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