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The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity

The infected cell protein 0 (ICP0) of herpes simplex virus 1, a promiscuous transactivator shown to enhance the expression of genes introduced into cells by infection or transfection, interacts with numerous cellular proteins and has been linked to the disruption of ND10 and degradation of several p...

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Autori principali: Van Sant, Charles, Hagglund, Ryan, Lopez, Pascal, Roizman, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC37518/
https://ncbi.nlm.nih.gov/pubmed/11447293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161283098
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