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RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit

The RPN4 (SON1, UFD5) protein of the yeast Saccharomyces cerevisiae is required for normal levels of intracellular proteolysis. RPN4 is a transcriptional activator of genes encoding proteasomal subunits. Here we show that RPN4 is required for normal levels of these subunits. Further, we demonstrate...

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Hlavní autoři: Xie, Youming, Varshavsky, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC30606/
https://ncbi.nlm.nih.gov/pubmed/11248031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071022298
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