RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit
The RPN4 (SON1, UFD5) protein of the yeast Saccharomyces cerevisiae is required for normal levels of intracellular proteolysis. RPN4 is a transcriptional activator of genes encoding proteasomal subunits. Here we show that RPN4 is required for normal levels of these subunits. Further, we demonstrate...
Guardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248031/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071022298 |
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