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RanGTP-Binding Protein NXT1 Facilitates Nuclear Export of Different Classes of RNA In Vitro

To better characterize the mechanisms responsible for RNA export from the nucleus, we developed an in vitro assay based on the use of permeabilized HeLa cells. This new assay supports nuclear export of U1 snRNA, tRNA, and mRNA in an energy- and Xenopus extract-dependent manner. U1 snRNA export requi...

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Detalhes bibliográficos
Main Authors: Ossareh-Nazari, Batool, Maison, Christèle, Black, Ben E., Lévesque, Lyne, Paschal, Bryce M., Dargemont, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85847/
https://ncbi.nlm.nih.gov/pubmed/10848583
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