Facilitated Nucleocytoplasmic Shuttling of the Ran Binding Protein RanBP1

The Ran binding protein RanBP1 is localized to the cytosol of interphase cells. A leucine-rich nuclear export signal (NES) near the C terminus of RanBP1 is essential to maintain this distribution. We now show that RanBP1 accumulates in nuclei of cells treated with the export inhibitor, leptomycin B,...

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Main Authors: Plafker, Kendra, Macara, Ian G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Nucleocytoplasmic Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85643/
https://ncbi.nlm.nih.gov/pubmed/10779340
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