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Facilitated Nucleocytoplasmic Shuttling of the Ran Binding Protein RanBP1

The Ran binding protein RanBP1 is localized to the cytosol of interphase cells. A leucine-rich nuclear export signal (NES) near the C terminus of RanBP1 is essential to maintain this distribution. We now show that RanBP1 accumulates in nuclei of cells treated with the export inhibitor, leptomycin B,...

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Publicat a:Mol Cell Biol
Autors principals: Plafker, Kendra, Macara, Ian G.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779340/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.10.3510-3521.2000
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