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Facilitated Nucleocytoplasmic Shuttling of the Ran Binding Protein RanBP1

The Ran binding protein RanBP1 is localized to the cytosol of interphase cells. A leucine-rich nuclear export signal (NES) near the C terminus of RanBP1 is essential to maintain this distribution. We now show that RanBP1 accumulates in nuclei of cells treated with the export inhibitor, leptomycin B,...

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Hlavní autoři: Plafker, Kendra, Macara, Ian G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85643/
https://ncbi.nlm.nih.gov/pubmed/10779340
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