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Ca(2+)-Dependent Nuclear Export Mediated by Calreticulin

We have characterized a pathway for nuclear export of the glucocorticoid receptor (GR) in mammalian cells. This pathway involves the Ca(2+) -binding protein calreticulin (CRT), which directly contacts the DNA binding domain (DBD) of GR and facilitates its delivery from the nucleus to the cytoplasm....

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Holaska, James M., Black, Ben E., Rastinejad, Fraydoon, Paschal, Bryce M.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12167720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.17.6286-6297.2002
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