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Ca(2+)-Dependent Nuclear Export Mediated by Calreticulin
We have characterized a pathway for nuclear export of the glucocorticoid receptor (GR) in mammalian cells. This pathway involves the Ca(2+) -binding protein calreticulin (CRT), which directly contacts the DNA binding domain (DBD) of GR and facilitates its delivery from the nucleus to the cytoplasm....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133999/ https://ncbi.nlm.nih.gov/pubmed/12167720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6286-6297.2002 |
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