Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

DNA interstrand cross-links (ICLs) represent lethal DNA damage, because they block transcription, replication, and segregation of DNA. Because of their genotoxicity, agents inducing ICLs are often used in antitumor therapy. The repair of ICLs is complex and involves proteins belonging to nucleotide...

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Ngā taipitopito rārangi puna kōrero
I whakaputaina i:	Mol Cell Biol
Ngā kaituhi matua:	Dronkert, Mies L. G., de Wit, Jan, Boeve, Miranda, Vasconcelos, M. Luisa, van Steeg, Harry, Tan, T. L. Raoul, Hoeijmakers, Jan H. J., Kanaar, Roland
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Taylor & Francis 2000
Ngā marau:	DNA Dynamics and Chromosome Structure
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4553-4561.2000
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Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

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