Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

DNA interstrand cross-links (ICLs) represent lethal DNA damage, because they block transcription, replication, and segregation of DNA. Because of their genotoxicity, agents inducing ICLs are often used in antitumor therapy. The repair of ICLs is complex and involves proteins belonging to nucleotide...

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Publikašuvnnas:	Mol Cell Biol
Váldodahkkit:	Dronkert, Mies L. G., de Wit, Jan, Boeve, Miranda, Vasconcelos, M. Luisa, van Steeg, Harry, Tan, T. L. Raoul, Hoeijmakers, Jan H. J., Kanaar, Roland
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Taylor & Francis 2000
Fáttát:	DNA Dynamics and Chromosome Structure
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4553-4561.2000
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