Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

DNA interstrand cross-links (ICLs) represent lethal DNA damage, because they block transcription, replication, and segregation of DNA. Because of their genotoxicity, agents inducing ICLs are often used in antitumor therapy. The repair of ICLs is complex and involves proteins belonging to nucleotide...

Повний опис

Збережено в:

Бібліографічні деталі
Опубліковано в::	Mol Cell Biol
Автори:	Dronkert, Mies L. G., de Wit, Jan, Boeve, Miranda, Vasconcelos, M. Luisa, van Steeg, Harry, Tan, T. L. Raoul, Hoeijmakers, Jan H. J., Kanaar, Roland
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Taylor & Francis 2000
Предмети:	DNA Dynamics and Chromosome Structure
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4553-4561.2000
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!

Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

Схожі ресурси