Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

DNA interstrand cross-links (ICLs) represent lethal DNA damage, because they block transcription, replication, and segregation of DNA. Because of their genotoxicity, agents inducing ICLs are often used in antitumor therapy. The repair of ICLs is complex and involves proteins belonging to nucleotide...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dronkert, Mies L. G., de Wit, Jan, Boeve, Miranda, Vasconcelos, M. Luisa, van Steeg, Harry, Tan, T. L. Raoul, Hoeijmakers, Jan H. J., Kanaar, Roland
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4553-4561.2000
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!