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Replication Delay along FRA7H, a Common Fragile Site on Human Chromosome 7, Leads to Chromosomal Instability

Common fragile sites are specific chromosomal loci that show gaps, breaks, or rearrangements in metaphase chromosomes under conditions that interfere with DNA replication. The mechanism underlying the chromosomal instability at fragile sites was hypothesized to associate with late replication time....

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Autori principali: Hellman, Asaf, Rahat, Ayelet, Scherer, Stephen W., Darvasi, Ariel, Tsui, Lap-Chee, Kerem, Batsheva
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC85809/
https://ncbi.nlm.nih.gov/pubmed/10825205
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