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Replication Delay along FRA7H, a Common Fragile Site on Human Chromosome 7, Leads to Chromosomal Instability

Common fragile sites are specific chromosomal loci that show gaps, breaks, or rearrangements in metaphase chromosomes under conditions that interfere with DNA replication. The mechanism underlying the chromosomal instability at fragile sites was hypothesized to associate with late replication time....

詳細記述

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書誌詳細
主要な著者: Hellman, Asaf, Rahat, Ayelet, Scherer, Stephen W., Darvasi, Ariel, Tsui, Lap-Chee, Kerem, Batsheva
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC85809/
https://ncbi.nlm.nih.gov/pubmed/10825205
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