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Continuous chromosomal instability in human pluripotent stem cells – the role of DNA replication
Human pluripotent stem cells (hPSCs) frequently acquire chromosomal aberrations, including aneuploidy, during culture. Recently, we identified a replication stress-based mechanism leading to ongoing chromosomal instability in aneuploid hPSCs that may also operate during the initiation of instability...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972117/ https://ncbi.nlm.nih.gov/pubmed/27652327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1183743 |
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