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Late Replication of the Inactive X Chromosome Is Independent of the Compactness of Chromosome Territory in Human Pluripotent Stem Cells

Dosage compensation of the X chromosomes in mammals is performed via the formation of facultative heterochromatin on extra X chromosomes in female somatic cells. Facultative heterochromatin of the inactivated X (Xi), as well as constitutive heterochromatin, replicates late during the S-phase. It is...

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Main Authors: Panova, A. V., Nekrasov, E. D., Lagarkova, M. A., Kiselev, S. L., Bogomazova, A. N.
Formato: Artigo
Idioma:Inglês
Publicado: A.I. Gordeyev 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695353/
https://ncbi.nlm.nih.gov/pubmed/23819036
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