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Nucleosides Rescue Replication-Mediated Genome Instability of Human Pluripotent Stem Cells
Human pluripotent stem cells (PSCs) are subject to the appearance of recurrent genetic variants on prolonged culture. We have now found that, compared with isogenic differentiated cells, PSCs exhibit evidence of considerably more DNA damage during the S phase of the cell cycle, apparently as a conse...
Zapisane w:
| Wydane w: | Stem Cell Reports |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7355123/ https://ncbi.nlm.nih.gov/pubmed/32413278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.04.004 |
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