Regulation of Cyclooxygenase 2 mRNA Stability by the Mitogen-Activated Protein Kinase p38 Signaling Cascade

A tetracycline-regulated reporter system was used to investigate the regulation of cyclooxygenase 2 (Cox-2) mRNA stability by the mitogen-activated protein kinase (MAPK) p38 signaling cascade. The stable β-globin mRNA was rendered unstable by insertion of the 2,500-nucleotide Cox-2 3′ untranslated r...

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Hlavní autoři: Lasa, Marina, Mahtani, Kamal R., Finch, Andrew, Brewer, Gary, Saklatvala, Jeremy, Clark, Andrew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85794/
https://ncbi.nlm.nih.gov/pubmed/10825190
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