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Regulation of Cyclooxygenase 2 mRNA Stability by the Mitogen-Activated Protein Kinase p38 Signaling Cascade

A tetracycline-regulated reporter system was used to investigate the regulation of cyclooxygenase 2 (Cox-2) mRNA stability by the mitogen-activated protein kinase (MAPK) p38 signaling cascade. The stable β-globin mRNA was rendered unstable by insertion of the 2,500-nucleotide Cox-2 3′ untranslated r...

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Sparad:
I publikationen:Mol Cell Biol
Huvudupphov: Lasa, Marina, Mahtani, Kamal R., Finch, Andrew, Brewer, Gary, Saklatvala, Jeremy, Clark, Andrew R.
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis 2000
Ämnen:
Gene Expression
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85794/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4265-4274.2000
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